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Orthocell at forefront of growing market opportunity in regenerative musculoskeletal treatment

Orthocell Ltd (ASX:OCC) is confident that its unique regenerative medicine product portfolio can address growing market opportunities in the treatment of complex musculoskeletal disorders.

The company is pursuing a total addressable market for CelGro® and Ortho-ATI® of US$10 billion and US$7.7 billion respectively – representing a combined US$17.7 billion per annum.

This market is driven by the rising rate of musculoskeletal disorders and demand for efficient and cost-effective treatments.

CelGro® nerve repair[hhmc]
The companys CellGro collagen medical device is designed to augment surgical repair of soft tissue and represents a breakthrough is soft tissue reconstruction.

It has multiple applications in nerve, tendon and bone repair which have been demonstrated as having superior clinical performance when compared to current market leading product.

CelGro nerve repair market opportunity.

Addressable market opportunities[hhmc]
CelGro has significant global commercial potential in..

Orthocell Ltd (ASX:OCC) is confident that its unique regenerative medicine product portfolio can address growing market opportunities in the treatment of complex musculoskeletal disorders.

The company is pursuing a total addressable market for CelGro® and Ortho-ATI® of US$10 billion and US$7.7 billion respectively – representing a combined US$17.7 billion per annum.

This market is driven by the rising rate of musculoskeletal disorders and demand for efficient and cost-effective treatments.

CelGro® nerve repair


The companys CellGro collagen medical device is designed to augment surgical repair of soft tissue and represents a breakthrough is soft tissue reconstruction.

It has multiple applications in nerve, tendon and bone repair which have been demonstrated as having superior clinical performance when compared to current market leading product.

CelGro nerve repair market opportunity.

Addressable market opportunities


CelGro has significant global commercial potential in its existing addressable markets as well as much wider applications in general surgical and soft tissue reconstruction applications.

Nerve regeneration has a US$7.5 billion addressable market, tendon and ligaments have a US$1.4 billion addressable market and bone regeneration has a US$1 billion addressable market.

The company is also executing a strategy to engage a global partner to manage the distribution and marketing of CelGro for dental bone and soft tissue repair procedures.

In addition, the company has identified that there has been very little innovation in the biologics membrane market resulting in a lack of product differentiation which represents an addressable market of more than US$1 billion per annum.

Pathway to US market


Orthocell has achieved initial EU approval for the product and with the safety and efficiency of the CelGro nerve repair product established, the company is now focused on executing its regulatory program to gain approval in the US.

The company is focused on the US 510(k) study which aims to support an evaluation of substantial equivalence to an approved nerve repair device (meeting the requirements of the US 510(k) predicate product regulatory pathway).

The US FDA pre-submission meeting has been completed, and ethics approval granted.

Surgical procedures will commence in quarter four 2020 with the target for the final data read out of quarter four 2021.

The addressable market for Ortho-ATI is estimated at greater than US$7.7 billion per annum.

Ortho-ATI® therapy


The Ortho-ATI cell therapy for tendon regeneration is an injectable clinical stage cellular therapy for treatment of chronic tendon injuries. It can be utilised at multiple tendon sites including shoulder, elbow, hip, hamstring and achilles.

The therapy addressed an unmet clinical need for a safe, effective, and non-surgical option and is the first injectable cellular therapy in orthopaedics for tendon regeneration.

Ortho-ATI also has extensive clinical validation with more than 690 patients treated to date.

Multiple addressable markets


Ortho-ATI is at the forefront of a large and growing market opportunity where the addressable market is estimated to be greater than US$7.7 billion per annum.

This included tennis elbow Read More – Source

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Argonaut Resources directors show faith in company by participating in oversubscribed SPP

Argonaut Resources NL (ASX:ARE) directors have demonstrated their faith in the company’s copper-zinc strategy by participating in the recently closed share purchase plan (SPP).

Independent non-executive chairman Patrick Elliot purchased more than 4.465 million shares at 0.55 cents per share in an indirect interest.

He now holds 5,876,159 shares in that interest with another 20,324,574 held in a separate indirect interest.

Independent non-executive chairman Malcolm Richmond acquired more than 5.454 million shares in a direct interest, increasing the number held in this interest to almost 15 million with another 1 million held in an indirect interest.

Overwhelming response to SPP[hhmc]
The company was overwhelmed by the response to its SPP which closed early and more than twice oversubscribed with the target subsequently increased to $2.5 million from $1.2 million.

Subscriptions in excess of $3 million were received and as a result, the SPP was closed with immediate effect.

Money ..

Argonaut Resources NL (ASX:ARE) directors have demonstrated their faith in the company’s copper-zinc strategy by participating in the recently closed share purchase plan (SPP).

Independent non-executive chairman Patrick Elliot purchased more than 4.465 million shares at 0.55 cents per share in an indirect interest.

He now holds 5,876,159 shares in that interest with another 20,324,574 held in a separate indirect interest.

Independent non-executive chairman Malcolm Richmond acquired more than 5.454 million shares in a direct interest, increasing the number held in this interest to almost 15 million with another 1 million held in an indirect interest.

Overwhelming response to SPP


The company was overwhelmed by the response to its SPP which closed early and more than twice oversubscribed with the target subsequently increased to $2.5 million from $1.2 million.

Subscriptions in excess of $3 million were received and as a result, the SPP was closed with immediate effect.

Money raised under this SPP and from the recently completed $2.7 million share placeRead More – Source

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Strickland Metals shares jump 39% ahead of drilling base metal target near DeGrussa

Strickland Metals Ltd (ASX:STK) shares surged 39% today ahead of its maiden drilling program at the Doolgunna Project, which will include a diamond drilling program that is likely to begin by the end of this month.

As a part of the program, a minimum of four diamond holes will be drilled to a depth of 500 metres to test a VMS target similar to the nearby DeGrussa deposit of Sandfire Resources (ASX:SFR).

Heritage survey[hhmc]
Exploration activity has recommenced on the Doolgunna Project following completion of heritage surveys to allow land access to areas where the company wishes to complete exploration drilling.

The target for drilling is a compelling base metal prospect that exhibits geological characteristics that are interpreted to be similar to Sandfire Resources’ DeGrussa deposit about 30 kilometres to the east of the project.

The prospect has a 3-kilometre-long electromagnetic conductor that lies below an outcropping copper-zinc gossan that has been mapped over a 1.2-kilomet..

Strickland Metals Ltd (ASX:STK) shares surged 39% today ahead of its maiden drilling program at the Doolgunna Project, which will include a diamond drilling program that is likely to begin by the end of this month.

As a part of the program, a minimum of four diamond holes will be drilled to a depth of 500 metres to test a VMS target similar to the nearby DeGrussa deposit of Sandfire Resources (ASX:SFR).

Heritage survey


Exploration activity has recommenced on the Doolgunna Project following completion of heritage surveys to allow land access to areas where the company wishes to complete exploration drilling.

The target for drilling is a compelling base metal prospect that exhibits geological characteristics that are interpreted to be similar to Sandfire Resources’ DeGrussa deposit about 30 kilometres to the east of the project.

The prospect has a 3-kilometre-long electromagnetic conductor that lies below an outcropping copper-zinc gossan that has been mapped over a 1.2-kilometre strike.

Diamond core drilling


The company plans to start the diamond core drilling by the end of this month.

A multi-purpose drill rig has been contracted to enable the minimum planned program wRead More – Source

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Pan Asia Metals has positive discussions on plans for Thai lithium project

Pan Asia Metals Ltd (ASX:PAM) has had positive discussions with authorities in Phang Nga Province, Thailand, including the provincial government, for its Reung Kiet Lithium Project.

PAM has submitted a presentation covering all aspects of the project including methods of ongoing exploration, conceptual mining and concentrate production, and the potential for downstream value-adding industries in Phang Nga and Thailand.

The presentation and subsequent discussions were aimed at assisting Phang Nga Provincial Government in their considerations for the proposed mining and industrial development areas.

Provincial Government discussions[hhmc]
Pan Asia was recently invited by the chief executive officer of the Phang Nga Provincial Administrative Organisation (PAO), a Phang Nga Provincial Government coordinating body, to represent PAM and the Reung Kiet Lithium Project.

The meeting was also attended by the head of Phang Nga Provincial Industry along with the representatives of the Phang Ng..

Pan Asia Metals Ltd (ASX:PAM) has had positive discussions with authorities in Phang Nga Province, Thailand, including the provincial government, for its Reung Kiet Lithium Project.

PAM has submitted a presentation covering all aspects of the project including methods of ongoing exploration, conceptual mining and concentrate production, and the potential for downstream value-adding industries in Phang Nga and Thailand.

The presentation and subsequent discussions were aimed at assisting Phang Nga Provincial Government in their considerations for the proposed mining and industrial development areas.

Provincial Government discussions


Pan Asia was recently invited by the chief executive officer of the Phang Nga Provincial Administrative Organisation (PAO), a Phang Nga Provincial Government coordinating body, to represent PAM and the Reung Kiet Lithium Project.

The meeting was also attended by the head of Phang Nga Provincial Industry along with the representatives of the Phang Nga Provincial Public Works and Town Planning Office.

Phang Nga Provincial Industry head has been appointed by the Phang Nga governor as chairman of the Phang Nga New Town Planning Committee.

During the meeting, the chairman of the committee conveyed its support for the Reung Kiet Lithium Project.

PAO wants to ensure that the requirements of the Reung Kiet project are incorporated into the town planning committee’s zoning plans to ensure that the project can progress once exploration and feasibility results prove positive.

“Can bring opportunities”


PAM managing director Paul Lock said: “We have been working hard in Phang Nga province and we are very happy with the positive reception that the Reung Kiet Lithium Project is receiving from the Phang Nga Provincial Government and surrounding communities.

“Reung Kiet is strategically located and based on peer feasibility work the project is positioned to potentially be one of the lowest-cost suppliers of lithium chemicals in the global peer group.

“This is a project that can bring substantial opportunities and value to Phang Nga and Thailand.”

Pan Asia is planning its second Reung Kiet drilling program with expectations that this will begin in the coming months following the conclusion of the current Khao Soon drilling program.

Potential cost curve leader


Reung Kiet is a hard rock project with lepidolite rich pegmatites chiefly composed of quartz, albite and lepidolite with minor cassiterite and tantalite as well as other accessory minerals including some rare earth.

Lepidolite does not require roasting and has a suite of by-products which are recoverable at the concentrator and processing stages of the flow sheet.

Peer feasibility work has Read More – Source

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